Abstract Background The extent of the consequences of an episode of severe acute kidney injury (AKI) on long-term outcome of critically ill patients remain debated.We conducted a prospective follow-up of patients included in a large multicenter clinical trial of renal replacement therapy (RRT) initiation strategy during severe AKI (the Artificial K
IL-6 is a central mediator of the immediate induction of hepatic acute phase proteins (APP) in the liver during infection and after injury, but increased IL-6 activity has been associated with multiple pathological conditions.In hepatocytes, IL-6 activates JAK1-STAT3 signaling that induces the negative feedback regulator SOCS3 and expression of APP
Music content annotation campaigns Jandy Energy Filter Parts are common on paid crowdsourcing platforms.Crowd workers are expected to annotate complex music artifacts, a task often demanding specialized skills and expertise, thus selecting the right participants is crucial for campaign success.However, there is a general lack of deeper understandin
Abstract Background The three-spined stickleback (Gasterosteus aculeatus) is a remarkable system to study the genetic mechanisms underlying parallel evolution during the transition from marine to freshwater habitats.Although the majority of previous studies on the parallel evolution of sticklebacks have mainly focused on postglacial freshwater popu